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urine sodium and potassium concentration to predict kidney failure in patients of severe infection in ICU

Urinary biochemistry as a marker of renal microcirculatory stress in sepsis: Prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/03/041334
Enrollment
111
Registered
2022-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B999- Unspecified infectious disease

Interventions

None listed

Sponsors

Department of Anesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: >18yrs of age with clinically suspected sepsis

Exclusion criteria

Exclusion criteria: 1) pre existing AKI or CKD 2) diuretic exposure 3) patients without indwelling catheter 4) surgery or trauma involving kidneys

Design outcomes

Primary

MeasureTime frame
To assess if 2 hour urinary potassium levels can predict development of AKI in sepsis patients Timepoint: 2hour urine electrolyte concentration is measured at a single point after onset of sepsis.

Secondary

MeasureTime frame
1)To assess correlation between urinary excretion of potassium and urinary excretion of sodium and measured 2hour creatinine clearance. 2)To assess correlation between urinary excretion of sodium and measured 2hour creatinine clearance. 3)To assess the ability of the ratio of urinary potassium to urinary creatinine in predicting AKI. 4)To assess the ability of 2hour urinary potassium levels and the ratio of urinary potassium to urinary creatinine in predicting requirement of RRT. 5)To assess the ability of fractional excretion of sodium and fractional excretion of potassium in predicting AKI Timepoint: Daily followup of creatinine and urine output to determine AKI

Countries

India

Contacts

Public ContactH R Rajathadri

AIIMS-Newdelhi

drrajathadri@gmail.com9886936414

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026