A study to check the results of two procedures for the inflammation of tooth pulp in which, one of the procedure involves half of the root canal procedure and the other one without root canal procedure

A STUDY TO ASSESS THE OUTCOME OF COMBINATION OF NON-SURGICAL ENDODONTIC THERAPY AND VITAL PULP THERAPY IN COMPARISON TO FULL PULPOTOMY PERFORMED IN MATURE PERMANENT MANDIBULAR MOLAR TEETH WITH SYMPTOMATIC IRREVERSIBLE PULPITIS AND PERIAPICAL RAREFACTION- A RANDOMIZED CONTROLLED TRIAL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/041298

Enrollment

Registered

2022-03-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis Health Condition 2: K040- Pulpitis

Interventions

Intervention1: pulpotomy: Full pulpotomy: The patient will be requested to rinse the oral cavity with 10 ml. of 0.2% chlorhexidine digluconate (Aster-X, Sandika pharmaceuticals Pvt. ltd. New Delhi).

time required to arrest the bleeding will be recorded. If the haemostasis will not achieved within 10 minutes, the tooth will be excluded from the study and standard root canal therapy will be carried

Eligibility

Inclusion criteria

Inclusion criteria: • Healthy patient of either gender between 18-45 years of age group. • Mandibular molar teeth with definitive clinical diagnosis of irreversible pulpitis with periapical involvement (PAI score >= 3) in either of the roots. • Positive response to either cold or EPT testing. • The tooth is restorable. • Probing pocket depth and mobility are within normal limits. • Cone Beam Computed Tomography records of the patient. Periapical lesion with PAI score >= 1 on CBCT will be taken.

Exclusion criteria

Exclusion criteria: • Teeth with definitive clinical diagnosis of irreversible Pulpitis which are not associated with periapical rarefaction.

Design outcomes

Primary

Measure	Time frame
a)Full pulpotomy b)Combination of non-surgical endodontic therapy and vital pulp therapy Clinical evaluation as well as radiographic evaluation ( including Intra oral peri apical radiograph and Cone beam computed tomography) were done to evaluate for periapical healing Timepoint: Day zero:- Inta-oral periapical radiograph and Cone beam computed tomography At six month follow-up:- Intra-oral periapical radiograph At Twelve month follow-up :- Intra-oral periapical radiograph and Cone beam computed tomography	—

Measure

Time frame

a)Full pulpotomy b)Combination of non-surgical endodontic therapy and vital pulp therapy Clinical evaluation as well as radiographic evaluation ( including Intra oral peri apical radiograph and Cone beam computed tomography) were done to evaluate for periapical healing Timepoint: Day zero:- Inta-oral periapical radiograph and Cone beam computed tomography At six month follow-up:- Intra-oral periapical radiograph At Twelve month follow-up :- Intra-oral periapical radiograph and Cone beam computed tomography

—

Secondary

Measure	Time frame
healing of periapical lesionTimepoint: 1 year	—

Countries

India

Contacts

Public ContactDr Aakash

All india institute of medical sciences, New delhi

dr.amritachawla@gmail.com9871445522

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026