Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: PEEP of 8 CmH2O plus 50% of abdominal pressure will be applied: Initially PEEP of 8 CmH2O will be applied after induction of anaesthesia and maintained up to five minutes after pneumope
lung will be recruited as per recruitment protocol. After lung recruitment PEEP of 8cmH20 + 50% of abdominal pressure will be applied. This PEEP will be maintained till deflation of pneumoperitoneum.
Sponsors
Rakesh Kumar
Eligibility
Inclusion criteria
Inclusion criteria: 1.Parents willing to give consent for inclusion in study 2. Children age more than one year and less than 12 years(1-12yrs). 3. American society of anaesthesiology(ASA) physical status less than IV. 4. Elective laparoscopic surgery of more than one hour of pneumoperitoneum and in lateral position
Exclusion criteria
Exclusion criteria: 1. Parental refusal to participate in the study. 2. Children with known severe lung disease. 3. Children with a history of severe lung infection having post infection sequelae in preoperative chest x-ray. 4. Children with known deformity of chest wall or thoracic spine. 5. Children with pre-existing significant cardiac, renal or hepatic diseases. 6. Children with history of previous thoracic surgery. 7. Children with BMI > 30 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in driving pressure in both groups at the end of pneumoperitonium.Timepoint: Change in driving pressure in the both groups at the end of pneumoperitoneum | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Peak airway pressure , Plateau pressure and mean airway pressure at the end of pneumoperitonium and 15 minutes interval during pneumoperitonium. 2.static lung compliance at the end of pneumoperitonium and 15 minutes interval during pneumoperitonium. 3.lung ultrasound score after induction and one hour after extubation. 4.PaO2/FiO2 ratio, alveolar-arterial oxygen gradient and PaCO2 and ETCO2 difference 5. Room air oxygen saturation 6. Incidence of intraoperative hypotension and Bradycardia Timepoint: 1 at end of pneumoperitoneum 2 at end of pneumoperitoneum 3 after induction and 1 hour post extubation 4after pneumoperitoneum and pneumoperitoneum deflation 5 post-op day 1or3 or at time of discharge whichever earlier 6. Intraoperative | — |
Countries
India
Contacts
Public ContactRakesh Kumar
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed