Health Condition 1: C64-C68- Malignant neoplasms of urinary tract Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Opioid free anaesthesia: Induction - Inj. Propofol 2mg/kg + Inj. Lignocaine 1.5mg/kg + Inj. Vecuronium 0.08mg/kg
Maintenance - Inhalational Agents + Epidural Bupivacaine 0.125% (1-10ml/
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: All adults aged 18-80 years, ASA I-II patients undergoing RCIC and RPLND
Exclusion criteria
Exclusion criteria: 1. Emergency surgeries 2. Major blood loss/Vascular reconstruction planned, increasing the possibility of/or in view of prolonged stay in ICU. 3. All contraindications/failure to establish epidural analgesia 4. All cases where epidural analgesia cannot be continued post-operatively 5. Pre-operatively on opioids (equivalent to 60 mg of oral morphine) for more than 1 week.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect of OFA on post-operative bowel activity assessed as time to passage of flatus /faeces in patients undergoing surgery for urological cancers (limited to RCIC and RPLND)Timepoint: At every 12 hour interval until bowel recovery | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the effect of OFA on the 1. Intra-operative hemodynamics 2. Quality of recovery 3. Post-operative pain score 4. Incidence of PONV 5. Length of hospital stay Timepoint: At every 12 hour interval until discharge from hospital | — |
Countries
India
Contacts
Public ContactDr Abhiram Y
Tata Memorial Centre
Outcome results
None listed