A clinical trial to study the efficacy of zinc sulphate mouthwash in oral mucositis patients who are receiving radiotherapy

Comparative efficacity of Zinc Sulphate Mouthwash vs Benzydamine mouthwash in oral mucositis patients

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/041185

Enrollment

Registered

2022-03-17

Start date

Unknown

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K123- Oral mucositis (ulcerative)

Interventions

Intervention1: Zinc sulphate mouthwash: Mouthwash contains zinc sulphate .15 ml thrice a day for 15 days. Route of administration is topical Control Intervention1: Benzydamine mouthwash: benzydamine m

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing to be a part of the study and sign the written informed consent. Patients with histologically confirmed head and neck carcinoma, planned for external beam radiotherapy with a total radiation dose ranging between 60-70 Gy and developed oral mucositis.

Exclusion criteria

Exclusion criteria: No previous history of radiotherapy of head and neck. Any oral ulcers and mucositis developed before starting radiotherapy

Design outcomes

Primary

Measure	Time frame
To evaluate the effectiveness of Zinc sulphate mouthwash using WHO oral mucositis assessment scaleTimepoint: All patients were evaluated in 3rd,6th,9th,12th and 15th day	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactRenuka Devi KR

JSS DENTAL COLLEGE AND HOSPITAL,JSS ACADEMY OF HIGHER EDUCATION (JSSAHER), MYSURU

dr.karthikeyapatil@jssuni.edu.in9449822498

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026