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A Clinical Trial to Compare the Effects of Nalbuphine and Dexmedetomidine along with Bupivacaine and Bupivacaine alone for Spinal Anaesthesia in Patients undergoing Orthopaedic Surgeries

Intrathecal Nalbhuphine and Dexmedetomidine as Adjuvant to Bupivacaine versus Plain Bupivacaine for Orthopaedic Surgeries under Subarachnoid Block - A Comparitive Study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041142
Enrollment
60
Registered
2022-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nalbuphine and Dexmedetomidine: Versus placebo Intervention2: Nalbuphine,: Nalbuphine 1.5 mg INTRATHECAL Control Intervention1: Dexmedetomidine: 10mcg INTRATHECAL Control Intervention2:

Sponsors

Dr Vinay B R
Lead Sponsor
Dr Dayananda V P
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective lower limb orthopaedic surgeries of 18-60 yrs of age under spinal anaesthesia, Surgeries lasting for 90-120 mins. Patients of ASA 1

Exclusion criteria

Exclusion criteria: Patients refusing to give consent for study, allergy to drugs, poly trauma and associated injuries

Design outcomes

Primary

MeasureTime frame
1) sensory blockade with respect to onset,maximum level attained, time taken for sensory regression and total duration of sensory blockade. 2) motor blockade with respect to onset,maximum level attained,quality of motor blockade and total duration of motor blockade. 3) total duration of analgesiaTimepoint: 4hrs—

Secondary

MeasureTime frame
Duration of post operative analgesia, side effects of drugsTimepoint: 4 hrs—

Countries

India

Contacts

Public ContactDr Dayananda V P

Bangalore Medical College and Research Institute

vpd921@yahoo.com9845161826

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026