Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age between 18-65 years, 2) Patients who have been in an intubated state since a minimum of 48 hours, 3) Excessive tracheobronchial secretions not present, 4) The underlying critical illness (their reason for intubation) must have been resolved, 5) Patients fulfilling the criteria of conventional methods for weaning from mechanical ventilation.
Exclusion criteria
Exclusion criteria: 1) Hemodynamic instability requiring vasopressors, 2) Gas exchange impairment requiring positive end- expiratory pressure (PEEP) >10 cmH2O and/or FIO2 > 50% to obtain a PaO2 > 60 mmHg, 3) Pressure support (PS) level > 20 cmH2O, 4) Deep sedation, 5) History of chronic obstructive pulmonary disease, neuromuscular disease, anatomical malformation of the diaphragm or use of muscle paralyzing agents, aminoglycosides and corticosteroids, 6) Pneumothorax or pneumomediastinum, increased intra-abdominal pressure, 7) Aseptic dressings over the chest that can hamper the process of ultrasonography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Sensitivity and specificity of USG indices as predictors of weaning outcome. 2. Positive predictive value (PPV), Negative predictive value (NPV) and diagnostic accuracy of USG indices as predictors of weaning outcome. Timepoint: To check if patient got reintubated within 48 hours post extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparison of traditional indices such as RSBI with USG indices as predictors of difficult weaningTimepoint: checking for reintubation within 48 hours after extubation | — |
Countries
India
Contacts
Himalayan institute of medical sciences