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Checking the efficacy of lung and diaphragm ultrasonography in weaning of patients from mechanical ventilation in intensive care settings

Use of lung and diaphragm ultrasonography as non-invasive indicators of weaning outcome in intensive care settings: An observational cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/03/041133
Enrollment
100
Registered
2022-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: ULTRASONOGRAPHY: ULTRASONOGRAPHY OF LUNGS AND DIAPHRAGM

Sponsors

Himalayan Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age between 18-65 years, 2) Patients who have been in an intubated state since a minimum of 48 hours, 3) Excessive tracheobronchial secretions not present, 4) The underlying critical illness (their reason for intubation) must have been resolved, 5) Patients fulfilling the criteria of conventional methods for weaning from mechanical ventilation.

Exclusion criteria

Exclusion criteria: 1) Hemodynamic instability requiring vasopressors, 2) Gas exchange impairment requiring positive end- expiratory pressure (PEEP) >10 cmH2O and/or FIO2 > 50% to obtain a PaO2 > 60 mmHg, 3) Pressure support (PS) level > 20 cmH2O, 4) Deep sedation, 5) History of chronic obstructive pulmonary disease, neuromuscular disease, anatomical malformation of the diaphragm or use of muscle paralyzing agents, aminoglycosides and corticosteroids, 6) Pneumothorax or pneumomediastinum, increased intra-abdominal pressure, 7) Aseptic dressings over the chest that can hamper the process of ultrasonography.

Design outcomes

Primary

MeasureTime frame
1. Sensitivity and specificity of USG indices as predictors of weaning outcome. 2. Positive predictive value (PPV), Negative predictive value (NPV) and diagnostic accuracy of USG indices as predictors of weaning outcome. Timepoint: To check if patient got reintubated within 48 hours post extubation

Secondary

MeasureTime frame
1. Comparison of traditional indices such as RSBI with USG indices as predictors of difficult weaningTimepoint: checking for reintubation within 48 hours after extubation

Countries

India

Contacts

Public ContactDr Poorva Goyal

Himalayan institute of medical sciences

poorvagoyal.020595@gmail.com7895413661

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026