Health Condition 1: L00-L08- Infections of the skin and subcutaneous tissue Health Condition 2: L089- Local infection of the skin and subcutaneous tissue, unspecified Health Condition 3: L768- Other intraoperative and postprocedural complications of skin and subcutaneous tissue
Conditions
Interventions
Intervention1: Kadermin (silver nanoparticle) cream: Kadermin cream arm: The Kadermin (silver nanoparticle) cream shall be applied topically on the wounds at 1gm/cm2 dosage daily once for minimum of 5
Sponsors
Kalinga Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female patients aged more than 18 years of age 2. Patients admitted with infected wound with swab/pus/tissue culture positive for a bacteria 3. Wound of any type and any area (body part) including either post-surgery, trauma, burn or chronic underlying illness like diabetes 4. Willingness to comply with study instructions for its duration as indicated by written informed consent from the patient
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women, 2. The wound with underlying cancer 3. Patients with underlying immunocompromised status (infected with HIV, any immunodeficiency) 4. Patient is sick enough requiring life support or vasopressors. 5. Participation in any clinical study, which may interfere with the current study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbiological clearance of the wound (bacteria isolated from the would swab)Timepoint: Day 5 and Day 10 | — |
Secondary
| Measure | Time frame |
|---|---|
| Wounds healing (presence necrotic tissue (slough/eschar), presence of pus/exudate, smell, wound bed colour, presence of granulation tissue, colour of epithelial tissue, and features of healing) and features of contraction Timepoint: DAY 10 | — |
Countries
India
Contacts
Public ContactDr Basanti Kumari Pathi
Kalinga Institute of Medical Sciences
Outcome results
None listed