Skip to content

A clinical study to compare Propofol and Etomidate in patients having systemic hypertension

Comparison of haemodynamic response to induction with Etomidate and Propofol in controlled hypertensive patient in a tertiary care center in Chengalpattu district - A randomized control trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041117
Enrollment
70
Registered
2022-03-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Etiomidate: Inj.etomidate 0.3mg/ kg as the induction agent during general anaesthesia in hypertensive patient Control Intervention1: Propofol: Inj. Propofol 2mg/kg as the induction agen

Sponsors

Dr P V Kavin Adhithya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient Aged between 18-60 years with Essential hypertension 2.Patients assessed as only ASA II (controlled hypertension)

Exclusion criteria

Exclusion criteria: 1.Patients undergoing emergency surgeries 2.Patients having co. morbid conditions including epilepsy, COPD etc. 3.Obstetric and pregnancy and lactating mothers 4.Obese patient (BMI >30kg/m2) 5.Patient with known drug allergies

Design outcomes

Primary

MeasureTime frame
To study the hemodynamic response (pulse rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure) when induced with propofol and etomidate in controlled hypertensive patient scheduled for elective surgery. Timepoint: 1min,2min,3min,4min,5min and 10min

Secondary

MeasureTime frame
â?¢ To study the incidence of any side effects of both the drugs peri-operatively. â?¢ To assess cost effectiveness of both drugs Timepoint: 10 Months

Countries

India

Contacts

Public ContactP V KAVIN ADHITHYA

Shri Sathya Sai Medical College and RI

drkrishna86@gmail.com9944579455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026