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Effect of oral clonidine premedication on intraoperative vital stability for patients undergoing laparoscopic cholecystectomy

Effect of oral clonidine premedication on perioprative hemodynamic response for patients undergoing laparoscopic cholecystectomy - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041080
Enrollment
100
Registered
2022-03-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitis Health Condition 2: K808- Other cholelithiasis

Interventions

Intervention1: Tablet clonidine 100 microgram: Group 1- tab clonidine 100mcg Group 2- placebo (tablet Rantac 100mg ) given 90 minutes before induction Control Intervention1: Tab Rantac 100mg: Tab Rant

Sponsors

Department of anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of ASA grade 1-2 2) Patients of both sex 3) Patients in age group 18-60 years 4) Patients scheduled for laparoscopic cholecystectomy surgeries

Exclusion criteria

Exclusion criteria: 1) Patients not fulfilling eligibility criteria 2) Lack of patient consent 3) Drug dependence 4) History of bronchial asthma 5) Patients allergic to clonidine 6) Hypertensive and diabetic patients 7) Severe coronary insufficiency, recent Myocardial infarction 8) Concomitant use of monoamine oxidase inhibitors, tricyclic antidepressantsor opioids

Design outcomes

Primary

MeasureTime frame
intra-operative haemodynamic parameters. Timepoint: Intraoperatively (90-120 minutes)—

Secondary

MeasureTime frame
Pain and sedation scores, duration of postoperative analgesia. Adverse effects Timepoint: 24 hours Postoperatively—

Countries

India

Contacts

Public ContactDr khemraj meena

Rnt medical college and mb hospital udaipur rajasthan

vreena112@gmail.com07300312714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026