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Comparison between two analgesic group of drugs in laproscopic renal surgeries

Analgesic, and Recovery profile comparison of Ketamine, Lignocaine, and Dexmedetomidine versus Fentanyl-based anaesthesia for Laparoscopic Renal Surgeries: A randomised, single-blind, pilot study - KeLiDex study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041065
Enrollment
20
Registered
2022-03-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N258- Other disorders resulting from impaired renal tubular function Health Condition 2: N258- Other disorders resulting from impaired renal tubular function Health Condition 3: N136- Pyonephrosis

Interventions

Intervention1: KELIDEX INFUSION: KETAMINE loading dose of 0.5mg/kg in 10 ml followed by KETAMINE infusion at 0.15mg/kg/hr, LIGNOCAINE infusion at 0.25mg/kg/hr AND DEXMEDETOMIDINE infusion at 0.2mcg/k

Sponsors

AIIMS Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: BMI BETWEEN 18.5-29.99KG/METER SQ, ELECTIVE LAPROSCOPIC RENAL SURGERIES

Exclusion criteria

Exclusion criteria: PATIENTS REFUSAL, PATIENTS WITH DIAGNOSIS OF SHOCK SEPSIS, PATIENTS WITH MAJOR SEVERE ORGAN FAILURE REQUIRING SUPPORT, PATIENTS WITH UNCONTROLLED HYPERTENSION ( >180/100), PATIENTS WITH SUSPECTED OR KNOWN AUTONOMIC NEUROPATHY , SPECIAL GROUP OF PARTICIPANTS, PREOPERATIVE BRADYCARDIA OR AV BLOCK, INTRAOPERATIVE CIRCUMSTANCES LIKE VASOPRESSOR OR VASODILATION CIRCUMSTANCES,IF REQUIRED OR REQUIRING HYPOTENSIVE ANAESTHESIA AND AIRWAY MANAGEMENT REQUIRING UNCONVENTIONAL TECHNIQUE AND MODIFICATIONS OF INDUCTION AND OXYGENATION OR PATIENT IS NOT EXTUBATED TILL 6TH POST OPERATIVE PERIOD DUE TO NON INTERVENTION RELATED CAUSE WILL ALSO BE EXCLUDED

Design outcomes

Primary

MeasureTime frame
1.To compare the Recovery profile from general anaesthesia 2.To compare intraoperative hemodynamics variations (as a surrogate of adequate analgesia under controlled anaesthetic depth) between the groups Timepoint: 24hrs

Secondary

MeasureTime frame
1. To compare the post-extubation sedation and discharge readiness from PACU 2. To compare postoperative 24h pain and rescue analgesics consumption Timepoint: 24hrs

Countries

India

Contacts

Public ContactT C ARUN

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RAIPUR

drhabibkarim@gmail.com9916496362

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026