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A trial to assess the effectiveness of inhaled glycopyrrolate in improving the visual clarity during insertion of endotracheal tube with the help of fiberscope.

A randomised controlled trial to evaluate the effect of inhaled glycopyrrolate in improving the fibreoptic intubating conditions under general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041048
Enrollment
70
Registered
2022-03-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inhaled Glycopyrrolate 25 microgram per ml: nebulisation with Glycopyrrolate 8 ml(200 microgram) over 20 minutes before surgery Control Intervention1: 0.9% Normal saline: Nebulization w

Sponsors

AIIMS PATNA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status 1 and 2 of either sex undergoing elective surgery Age of 18 to 65 years Anticipated difficult airway in which fibreoptic intubation is planned under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients in which other modalities of intubation is planned Airway obstruction

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the degree of airway secretion with or without use of inhaled glycopyrrolate prior to fibreoptic intubationTimepoint: Intraoperative at the time of fibreoptic intubation—

Secondary

MeasureTime frame
Time to reach carina The change in heart rate and blood pressure 20 min after nebulization Incidence of laryngospasm or bronchospasm post extubationTimepoint: Intra operative during fibreoptic intubation. Preoperative after starting nebulization Post extubation—

Countries

India

Contacts

Public ContactDr M N Pradhan

AIIMS PATNA

drabhyu@gmail.com9013512403

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026