Health Condition 1: K508- Crohns disease of both small andlarge intestine
Conditions
Interventions
Intervention1: plant based diet: Patients will be given a plant-based diet chart accordingly and will be counselled
to adhere to the diet protocol. Regular telephonic interviews will be done to ensure
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 18 â?? 65 years 2. Patients with Crohnâ??s disease with CDAI ( 3. Patients with inflammatory phenotype (B1) 4. Patients who agree to adhere to the diet schedule 5. Patients on stable doses of azathioprine/ 6-mercaptoprine/ methotrexate for 6 months 6. Patients on stable doses of 5-ASA for 4 weeks
Exclusion criteria
Exclusion criteria: 1. Patients with severe disease activity 2. Patients with antibiotic or probiotic usage in the past 4 weeks 3. Patients with active perianal disease 4. Patients with abdominal abscess/ intestinal fistulae/ obstruction 5. Patients with symptomatic strictures 6. Patients with history of extensive colonic resection, subtotal or total colectomy7. Patients with ileostomy, colostomy, known fixed symptomatic stenosis or complex fistulae 8. Patients requiring or expected to require surgical intervention 9. Patients requiring hospitalization 10. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate effect of plant-based diet on gut microbiome in patients with Crohnâ??s disease in remissionTimepoint: Baseline, 48 weeks and during relapse | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate efficacy of plant-based diet in preventing relapse in patients with Crohnâ??s disease who are in clinical and biochemical remission 2. To evaluate tolerability of plant-based diet in patients with Crohnâ??s diseaseTimepoint: 1 year | — |
Countries
India
Contacts
Public ContactDrVineet Ahuja
All India Institute of Medical Sciences
Outcome results
None listed