Comparison between two drugs- dexmedetomidine and lidocaine, when administered via two routes- nebulized and intravenous as a premedication for awake fibreoptic intubation in attenuating the haemodynamic changes and for patient comfort

Comparison between nebulized dexmedetomidine- lidocaine mixture and intravenous dexmedetomidine- lidocaine nebulization as a premedication for awake fibreoptic intubation.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/041006

Enrollment

Registered

2022-03-11

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Prospective double blind study Nebulized dexmedetomidine - lidocaine group: Nebulization of 3ml 4% lignocaine along with nebulization of dexmedetomidine at 1 mcg/kg till it gets over Co

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 patients between 18 to 65 years planned for elective fibreoptic intubation in head and neck surgeries in Mazumdar Shaw Medical Centre, Bangalore

Exclusion criteria

Exclusion criteria: Patient refusal Pregnancy Known cardiac diseases including heart block Intracranial pathology and cerebrovascular diseases

Design outcomes

Primary

Measure	Time frame
Comparison of patient comfort in terms of cough scoreTimepoint: 10 minutes	—

Secondary

Measure	Time frame
Incidence of bradycardia and hypotensionTimepoint: 10 minutes	—

Countries

India

Contacts

Public ContactReshma Jose

Narayana Hrudayalaya Hospital

kadlinaveena@gmail.com7406396276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026