Comparing the pain relieving effect of fentanyl alone vs combination of fentanyl and morphine after cessarean delivery

Comparison of fentanyl alone vs combination of fentanyl and morphine as an adjuvant to 0.5% hyperbaric bupivacaine for spinal anaesthesia in patients undergoing elective cesarean section- A prospective Randomised controlled trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/040986

Enrollment

Registered

2022-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fentanyl: Fentanyl 20 mcg added to 0.5% hyperbaric Bupivacaine (1.8 ml) Intrathecal route Control Intervention1: Fentanyl and morphine: Fentanyl 20 mcg plus morphine 50 mcg added to 0.5

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients who are giving consent 2. All term ( >36 weeks) pregnant women 3. Patients with mild PIH, controlled gestational diabetes(ASA I and II) 4. Patients aged between 20-40 years 5. Singleton pregnancy 6. Patients who are coming for elective LSCS

Exclusion criteria

Exclusion criteria: 1. Patients not willing to give consent 2. Known allergy to amide local anesthetics, fentanyl and morphine 3. Patients with contraindications to sub arachnoid block. 4. Patients with cardiovascular disease, severe pre eclampsia, uncontrolled gestational diabetes, coagulopathies(ASA III and above) 5. Skin infection at block areas 6. Deformities of spinal column 7. Emergency LSCS

Design outcomes

Primary

Measure	Time frame
Duration of analgesiaTimepoint: Baseline, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours	—

Secondary

Measure	Time frame
NATimepoint: NA	—

Countries

India

Contacts

Public ContactAthisaya Elango

Sri Ramakrishna hospital

prabhadr01@gmail.com9791346959

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026