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Randomized Clinical trial to check the effects of intervention High Definition Transcranial Direct Current Stimulation on depressive and associated symptoms in Parkinsons Disease

Effect of high definition transcranial direct current stimulation on depressive and associated symptoms in Parkinsons disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/040966
Enrollment
24
Registered
2022-03-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G20- Parkinsons disease

Interventions

Intervention1: Effect of active HD-tDCS on depressive and associated symptoms in Parkinsons Disease: Active HD-tDCS:2 sessions of 20 minutes with 30 minutes interval in between. Control Intervention1

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Idiopathic PD,H & Y stage 2 & 3, 9-34 MADRS Score, right handedness, stable anti parkinson treatment for 1 month and written informed consent.

Exclusion criteria

Exclusion criteria: Patients with parkinsonism other than Idiopathic PD. Patients with Dementia. Patients with severe depression. Patients on psychotropics. Significant Head Injury. Pregnant females. Patients with relative contraindications to HD-tDCS.

Design outcomes

Primary

MeasureTime frame
effect on Depressive symptoms(MADRS), cognitive function(MoCA), motor symptoms, Non motor symptomsTimepoint: immediately and after 1 week—

Secondary

MeasureTime frame
Subjective mood change, HD-tDCS side effect, QoLTimepoint: POMS-VAS(immediately), HD-tDCS sideeffect checklist(immediately), Euro-Qol(1 week)—

Countries

India

Contacts

Public ContactPranshu Sharma

PGIMER, Chandigarh

pranshutrijal@gmail.com08146755835

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026