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Chest muscle function in patients during removal from ventilator in ICU

Determination of parasternal intercostal muscle activity in critically ill patients with various weaning patterns and its association with weaning-induced pulmonary oedema (WIPO)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/03/040965
Enrollment
145
Registered
2022-03-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J962- Acute and chronic respiratory failure

Interventions

None listed

Sponsors

Souvik Chaudhuri
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who were mechanically ventilated in ICU and meet the following criteria will be put on SBT for weaning will be included. Following will be the criteria to consider for weaning in the ICU which is used by any intensivist at our institute: 1. Fraction of inspired oxygen (FiO2 2. Positive end expiratory pressure (PEEP) 3. Partial pressure of oxygen in arterial blood (PaO2)/FiO2 > 150 mmHg 4. Respiratory rate 5. Tidal volume >5mL /kg, 6. Minute ventilation 7. No abnormality in electrolyte parameters, absence of hemodynamic instability, resolution of the initial cause of ventilator requirement and patients awake with the ability to cough.

Exclusion criteria

Exclusion criteria: 1. Patients with chest wall abnormalities, 2. Distorted chest wall anatomy, 3. Patients with any known neuromuscular weakness, 4. Patients with any known diaphragmatic disorders 5. Pregnant patients, 6. Patients with known cardiac dysfunction on initial ECHO during hospital admission 7. Any patient in whom the SBT is aborted even before 30 minutes duration as deemed by the intensivist will be excluded.

Design outcomes

Primary

MeasureTime frame
Successful weaning from ventilatorTimepoint: 48 hours after removal of ventilator

Secondary

MeasureTime frame
Survival of ICU stayTimepoint: 28 days from day of admission to ICU

Countries

India

Contacts

Public ContactSouvik Chaudhuri

Kasturba Medical College, Manipal, Manipal Academy of Higher Education

souvik.chaudhuri@manipal.edu9937178620

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026