Comparison of intrathecal 0.75% ropivacaine heavy against 0.5% bupivacaine heavy in lower abdominal and lower limb surgery

To compare efficacy of intrathecal 0.75% heavy ropivacaine against 0.5% bupivacaine heavy in lower abdominal and lower limb surgeries - RoBu

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/040955

Enrollment

Registered

2022-03-09

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ropivacaine 0.75% Heavy: efficacy of intrathecal 0.75% ropivacaine heavy 3 ml in lower abdominal and lower limb surgery Control Intervention1: Bupivacaine 0.5% Heavy: efficacy of intra

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing elective lower limb orthopedic and lower abdominal surgery under spinal anaesthesia having ASA status I & II, between age group of 20 to 50 yrs., with weight of 50 to 70 kg & height of 150 Ã¢â?¬â?? 170 cm of either sex.

Exclusion criteria

Exclusion criteria: Patients having contraindications to spinal anaesthesia & known drug allergy

Design outcomes

Primary

Measure	Time frame
Duration of onset of sensory level by pinprick upto L1 & Motor level by bromage scale of 3 of inability to move thigh, knee and ankle will be assessed. Peak sensory level achieved & ItÃ¢â?¬â?¢s duration will be assessed.Timepoint: Duration of onset of sensory level by pinprick upto L1 & Motor level by bromage scale of 3 of inability to move thigh, knee and ankle will be assessed every minute till end result. Peak sensory level achieved & ItÃ¢â?¬â?¢s duration will be assessed every minute till end result.	—

Measure

Time frame

Duration of onset of sensory level by pinprick upto L1 & Motor level by bromage scale of 3 of inability to move thigh, knee and ankle will be assessed. Peak sensory level achieved & ItÃ¢â?¬â?¢s duration will be assessed.Timepoint: Duration of onset of sensory level by pinprick upto L1 & Motor level by bromage scale of 3 of inability to move thigh, knee and ankle will be assessed every minute till end result. Peak sensory level achieved & ItÃ¢â?¬â?¢s duration will be assessed every minute till end result.

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Secondary

Measure	Time frame
Intra-opeative haemodyamic parameters (SBP, DBP, SPO2, RR) will be assessed every 5 min for 30 minutes & variation of Ã?Â± 30% will be marked. Also time of two segment sensory regression will be assessed. Post operatively duration of analegesia with first occurence of sensation of pain will be assessed. Side effects if any will be noticed.Timepoint: Hemodynamic Parameters Every 5 Minute, For 30 Minute. Occurrence of pain sensation every 5 min till pain complaint. Side effects monitored for 24 Hours.	—

Measure

Time frame

Intra-opeative haemodyamic parameters (SBP, DBP, SPO2, RR) will be assessed every 5 min for 30 minutes & variation of Ã?Â± 30% will be marked. Also time of two segment sensory regression will be assessed. Post operatively duration of analegesia with first occurence of sensation of pain will be assessed. Side effects if any will be noticed.Timepoint: Hemodynamic Parameters Every 5 Minute, For 30 Minute. Occurrence of pain sensation every 5 min till pain complaint. Side effects monitored for 24 Hours.

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Countries

India

Contacts

Public ContactDr Sandipbhai J Patel

GMC Jalgaon

sandip2027@yahoo.co.in7507271786

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026