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A study of the effect of magnetic stimulation of brain in amputees with pain

Effect of repetitive transcranial magnetic stimulation (rTMS) of dorsolateral prefrontal cortex (DLPFC) in patients with phantom limb pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/040920
Enrollment
56
Registered
2022-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G546- Phantom limb syndrome with pain

Interventions

Intervention1: Repetitive transcranial magnetic stimulation (rTMS): Repetitive transcranial magnetic stimulation is delivered by placing a coil over the scalp which delivers variable magnetic flux res

Sponsors

Akanksha principal investigator
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Willingness to participate in the study Traumatic amputation surgery of the limb Symptoms compatible with phantom limb pain

Exclusion criteria

Exclusion criteria: Presence of cardiac pacemaker, medical pumps, or implanted metals. Neuropsychiatric disorders that can affect the patient ability to consent to the study participation Diagnosis of epilepsy or cardiac disease Any pathology that could alter the course of phantom limb pain (diagnosis of cancer, immunological disorders, renal insufficiency requiring dialysis treatment, etc)

Design outcomes

Primary

MeasureTime frame
Pain status Psychiatric parameters (anxiety, depression, quality of life) Stress biomarkers (beta endorphin, cortisol)Timepoint: Pain status will be assessed at baseline and after each session of the 10 days of intervention. Psychiatric parameters will be assessed at baseline and after 10 days of intervention. Pain status and pyschiatric parameters will also be assessed on day 15, 30 and 60 of follow up. Stress Biomarkers samples will be collected at baseline, 5 days of intervention and 10 days intervention.

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr Akanksha

AIIMS, New Delhi

drakanksha111@gmail.com8377933797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026