Health Condition 1: N832- Other and unspecified ovarian cysts
Conditions
Interventions
Intervention1: Curcumin and life style modifications: Curcumin 500mg TDS and life style modifications for 3months
Control Intervention1: life style modifications: Life style modifications for 3 months
Sponsors
AIIMS RISHIKESH
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women with PCOS diagnosed by Rotterdam criteria. 2.Aged between 18-49 years 3. Patients who are willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with hormonal disorders, autoimmune diseases, cancer, diabetes mellitus. 2. Pregnancy and lactating females. 3. Hyperprolactinemia. 4. Patients taking OCPs, antioxidants, multivitamin mineral oils, statins, Anti TNF drugs, glucocorticoids (any intervention that could alter insulin sensitivity, inflammation, or oxidative stress status). 5. Overt infections. 6. Women presenting with Infertility.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Homeostatic model assessment - insulin resistance (HOMA-IR) calculated as FI (microU/l) Ã? FPG (nmol/l)/22.5 among both groups.Timepoint: at baseline and after 3 months of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| fasting plasma glucose, fasting insulin, QUICKI, LH, FSH, DHEAS, Testosterone, Hirsutism, Anthropometric parametersTimepoint: at baseline and after 3 months after intervention | — |
Countries
India
Contacts
Public ContactDr Kavita Khoiwal
AIIMS RISHIKESH
Outcome results
None listed