Health Condition 1: G318- Other specified degenerative diseases of nervous system
Conditions
Interventions
Intervention1: Transcranial direct current stimulation: 2mA of transcranial direct current stimulation for 30 minutes, single session
Control Intervention1: Transcranial direct current stimulation: Sh
Sponsors
National institute of Mental Health and Neurosciences Bangalore
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients > 50 years diagnosed with MCI as per NIAAA criteria 2. Right-handed individuals. 3. CDR â?? global score 0.5. 4. Patients meeting inclusion criteria recruited from geriatric psychiatry services, NIMHANS or community outreach activities. 5. Ability to give informed consent ascertained by a standardised assessment tool(Jeste et al., 2007) 6. Patients with chronic medical conditions that are stable
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with dementia. 2. Presence of other axis I mental illness 3. Patients diagnosed with reversible causes of MCI like hypothyroidism, Nutritional deficiencies, Subdural hematoma, chronic infections or NPH 4. H/o CVA, traumatic brain injury, epilepsy or Parkinsonian syndromes 5. Patients currently on antihistamines, anticholinergic drugs, sedatives or other such medications which interfere with cognitive functioning 6. Patients with substance use (not amounting to disorder) are not excluded but the data regarding the quantity of use will be collected
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference between groups in Oxygenated hemoglobin and deoxygenated hemoglobin concentrations measured by fNIRSTimepoint: Baseline and post tDCS session | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome: behavioral data during the verbal fluency task in fNIRSTimepoint: pre and post tDCS | — |
Countries
India
Contacts
Public ContactDr Subhashini K R
Department of Psychiatry, NIMHANS
Outcome results
None listed