Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous 1.5mg/kg lignocaine bolus and nebulized lignocaine-2% for 20 minutes.: Comparison of efficacy of nebulized lignocaine 2% for 20minutes with intravenous lignocaine 1.5mg/kg b
Sponsors
Government of Gujarat
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1 and 2 patients posted for surgery under general anaesthesia requiring endotracheal intubation.
Exclusion criteria
Exclusion criteria: Patients with pre existing hypertension, Patients with known allergy to the study drug or contraindication to any of the administered drugs, Patients with anticipated difficult airway, Patients who refused or inability to understand the procedure. 5. Patients who are smokers 6. Patients with History of respiratory distress 7. Patients with gastroesophageal reflux,Neurological ,cardiovascular,respiratory ,hepatic or renal dise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of efficacy of the NL as compared to IVL in suppressing pressor response to laryngoscopy and intubation Timepoint: Starting of nebulized lignocaine/Intravenous lignocaine to 20th minute after endotracheal intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of efficacy of the 2% lignocaine nebulization for 20minutes as compared to 1.5mg/kg intravenous lignocaine bolus in suppression of arrhythmias/any other complications if any during laryngoscopy and intubation. Timepoint: Preoperatively before induction starting of 2% nebulized lignocaine/1.5mg/kg Intravenous lignocaine upto 20 minutes after endotracheal intubation. | — |
Countries
India
Contacts
Public ContactDr Smita R Engineer
B.J medical College, Civil Hospital, Ahmedabad
Outcome results
None listed