Skip to content

Comparison of two drugs given during operation for prevention of discomfort related to urinary catheter postoperatively

Comparison of Intravenous Dexmedetomidine and Magnesium infusion for Prevention of Postoperative Catheter-Related Bladder Discomfort (CRBD) A Randomized, Double-Blind Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/040786
Enrollment
180
Registered
2022-03-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: IV Dexmedetomidine intra-operatively: Drug will be given intravenously at a loading dose of 1 mcg/kg over 10 minutes in 100 ml normal saline followed by 0.5 mcg/kg/hr infusion for the d

Sponsors

AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1-2, General Anaesthesia, Surgery duration 2-4 hours

Exclusion criteria

Exclusion criteria: Per-existing bladder disease, Urinary tract infection, Prostate disease, Urethral stricture, Any surgery involving bladder, Any surgery with epidural analgesia or other regional anaesthesia affecting bladder analgesia, pre-operative catheterisation, history of neuromuscular disorder, Calcium channel blocker medication, Hypermagnesemia, Bundle branch block.

Design outcomes

Primary

MeasureTime frame
Incidence of moderate to severe CRBDTimepoint: 0 hours( Immediate post-operative period)

Secondary

MeasureTime frame
Incidence of any side effectsTimepoint: Entire duration of patient monitoring;Incidence of moderate to severe CRBDTimepoint: 2,6 and 12 hours;Patient satisfaction scoreTimepoint: At 12 hours;Requirement of rescue drugTimepoint: In 12 hours;Sedation scoreTimepoint: 0 hours;Time to extubationTimepoint: Intra-operatively

Countries

India

Contacts

Public ContactAnkur Yadav

All India Institute of Medical Sciences Jodhpur

drrakeshspmc@gmail.com9460429221

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026