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comparison of intravenous vs intrathecal dexamethasone on prevention of post op nausea and vomiting in caesarean section

Comparison of the effect of intravenous and inrathecal dexamethasone on prevention of post op nausea and vomiting in patients posted for caesarean section

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/040772
Enrollment
90
Registered
2022-03-03
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Group B: The study will be conducted on patients undergoing CS under spinal anesthesia with local anaesthetic (LA) solution containing 1.5 ml bupivacaine heavy(0.5%). Before surgery, pa

Sponsors

AIIMS JODHPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant patients undergoing emergency/elective Cesarian Section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. Refusal of informed consent 2. Hemodynamic instability 3. Patients having an allergic reaction to steroids 4. Fever or infection 5. Patient with an underlying medical condition with long term use of steroids 6. Patients having pregnancy-associated complications(hyperemesis gravidarum) 7. History of gastrointestinal disorders, motion disorders 8. Use of an antiemetic drug received before surgery

Design outcomes

Primary

MeasureTime frame
The primary outcome is to find the efficacy of intravenous and intrathecal dexamethasone on preventing the PONV in pregnant patients undergoing caesarean section (CS) under spinal anaesthesia measured in terms of number of episodes of nausea and/or vomiting in 24 hours postoperatively.Timepoint: Episodes within 24 hrs

Secondary

MeasureTime frame
Total antiemetic consumption Onset of sensory block Duration of anesthesia Defined as time from onset of sensory block, to first rescue analgesic patient demand VAS3 Total analgesic consumption in 24 hours Quality of analgesia To assess the adverse effectsTimepoint: 24 HRS

Countries

India

Contacts

Public ContactDr Bharat Paliwal

AIIMS,Jodhpur

docbpali@gmail.com9588089378

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026