Health Condition 1: K729- Hepatic failure, unspecified
Conditions
Interventions
None listed
Sponsors
Mohamed Rela
Eligibility
Inclusion criteria
Inclusion criteria: Adult cases (18 years) First transplant DBD grafts DCD grafts (controlled and uncontrolled) DBD and DCD grafts managed by perfusion machines Living donor grafts (only right-side grafts)
Exclusion criteria
Exclusion criteria: Combined grafts (e.g., liver-kidney, liver-heart) Domino grafts Auxiliary grafts Double grafts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To develop new algorithms for the timely prediction of Allograft Failure at 90 and 365 days Timepoint: 90 days and 365 days | — |
Secondary
| Measure | Time frame |
|---|---|
| To validate the already existing predictive models To develop a novel time-based dynamic algorithm, with increasing accuracy from the 3rd to 7th post-operative day To investigate differences in the incidence of Allograft Failure at 90 and 365 days according to DBD, DCD, LD donor grafts; To evaluate the effect of mitigation strategies on the precipitating factors of Allograft Failure at 90 and 365 days To identify risk factors for mortality that may contraindicate re-transplant Timepoint: 3rd to 7th day 90 days and 365 days | — |
Countries
India
Contacts
Public ContactAshwin Rammohan
Dr. Rela Institute and Medical Centre
Outcome results
None listed