Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group M NE: patient will recieve Magnesium Sulphate nebulisation (30mg/kg) diluted to 5ml nebulised over 15 minutes and Normal saline 50ml via infusion pump over 15 minutes
Control Inte
Sponsors
none
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists Physical status (ASA) I-II Patients undergoing elective surgery under general anaesthesia requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: Anticipated Difficult laryngoscopy and intubation or more than one attempt for intubation taken. Patient having cardiovascular dysfunction. Uncontrolled Hypertensive Patients with raised intracranial pressure or intraocular pressure Pre-existing hepatic or renal impairment. Pregnant patients. Allergic to Study Drug. Patient refusal for consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in Mean Arterial Pressure and Heart Rate following intubationTimepoint: at the time of laryngoscopy, just after intubation, 1 min, 5 min and 10 min after intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| time taken to achieve TOF ratio of zeroTimepoint: during Induction;To compare propofol consumption during induction of anaesthesiaTimepoint: during induction;to look for incidence of bradycardia or hypotensionTimepoint: intraoperatively;to look for incidence of nausea or vomiting and respiratory depressionTimepoint: post operatively | — |
Countries
India
Contacts
Public ContactDr Priyanka Gupta
all india institute of medical sciences, rishikesh
Outcome results
None listed