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Study to evaluate iron oxide nanoparticles as suitable medicament in children teeth

Evaluation of magnetic nanoparticles as pulpotomy medicament in primary teeth randomised controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040656
Enrollment
48
Registered
2022-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Magnetic Nanoparticles: Magnetic nanoparticles are hydrophilic biocompatible antibacterial antimicrobial and antifungal inhibitory effect on the growth rate of Streptococcus mitis Strep

Sponsors

Dr Charul Kumari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The children in the range of 3-9 years of age Teeth with deep carious lesions which are restorable after completion of the procedure radiographically the caries should be approximating to the pulp Hemorrhage stoped within 5 minutes from the amputated pulp stumps using a sterile pledget of moist cotton

Exclusion criteria

Exclusion criteria: Patients with spontaneous pain and periapical radiolucency Patients with clinical radiographic signs of pulpal necrosis furcation involvement periapical pathology internal resorption calcification in canal Tooth having previously attempted pulpotomy or pulpectomy Patients with clinical signs or symptoms suggesting a nonvital tooth such as suppurating sinus soft tissue swelling Tooth with no permanent successor Immunocompromised patients (HIV Hepatitis B C Tuberculosis) and congenital heart defects History of cancer with in oral maxillofacial region

Design outcomes

Primary

MeasureTime frame
primary outcome will be seen 1 month after the trail which include pain swelling mobility percussion pain sinus tract premature tooth loss periodontal pocketTimepoint: 1 month

Secondary

MeasureTime frame
secondary outcomes will be seen 3 months and 6 months after the trail which include pain swelling mobility percussion pain sinus tract premature tooth loss periodontal pocketTimepoint: 3months 6months

Countries

India

Contacts

Public ContactRajeev Kumar Singh

King george medical college

rajkids2000@yahoo.co.in9450849528

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026