FindTrial
Sign In

Trial comparing the time of onset of muscle paralysis by two drugs

A randomised control study of Rocuronium with magnesium sulphate versus Succinylcholine on time of onset of paralysis in adult patient undergoing rapid sequence induction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040528
Enrollment
135
Registered
2022-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Rocuronium with Magnesium: Magnesium sulphate at a dose of 60mg/kg is given over 10 minutes prior to induction followed by Rocuronium at a dose of 0.9mg/kg is used for muscle relaxation

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective surgery under General anaesthesia with a duration of >60 minutes ASA status 1 and 2 patients Age 18-60 years

Exclusion criteria

Exclusion criteria: 1. ASA status 3 and 4 2. Patients with contraindications to any of the drugs used in this study 3. Patients with neuromuscular diseases 4. Patients with electrolyte imbalances 5. BMI >28 6. Anticipated difficult intubation or mask ventilation 7. Pregnancy 8. Emergency surgery

Design outcomes

Primary

MeasureTime frame
Time of disappearance of train of fourTimepoint: Baseline, Time taken for complete paralysis—

Secondary

MeasureTime frame
Intubation scoreTimepoint: Assessed during intubation;Laryngoscopy response by measuring pulse rate, Blood pressure, SpO2, respiratory rateTimepoint: Every minute from laryngoscopy, upto 10 minutes—

Countries

India

Contacts

Public ContactShagufta Naaz

AIIMS Patna

drshaguftanaaz@gmail.com7838117314

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026