Health Condition 1: G048- Other encephalitis, myelitis and encephalomyelitis
Conditions
Interventions
None listed
Sponsors
Prof Naveen Sankhyan
Eligibility
Inclusion criteria
Inclusion criteria: 1. Fulfilling the clinical diagnostic criteria of autoimmune encephalitis (Cellucci et al 2020) 2. No preexisting neurological disorder like epilepsy, cerebral palsy, neurometabolic disorder, movement disorder or degenerative brain disease
Exclusion criteria
Exclusion criteria: 1. No parental consent 2. Alternative disease diagnosed on follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validity (sensitivity, specificity)of PASS will be assessed by comparison with mRS and PedsQL score as per COnsensus-based Standards for the selection of health status Measurement INstruments(COSMIN) checklistTimepoint: 8 timepoints (Day7, day14, day 28 and then monthly till 6 months of presentation) | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of PASS will be assessed with CASE score and cognitive outcomeTimepoint: 6 months of presentation;Inter-rater agreement will be assessed using Kappa statisticTimepoint: NA;Internal consistency will be assessed by item-total correlation and Cronbach alphaTimepoint: NA;latent structure of these items using Restricted and non-restricted factor analytic modelsTimepoint: At the end of study | — |
Countries
India, United Kingdom
Contacts
Public ContactNaveen Sankhyan
PGIMER, Chandigarh
Outcome results
None listed