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Can perioperative infusion of magnesium sulfate reduce blood sugar levels in diabetic patients undergoing cardiac surgeries

The Effect of Perioperative Magnesium Sulfate on Blood Sugar in Patients with Diabetes Mellitus Undergoing Cardiac Surgery: A Double-Blinded Randomized Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040474
Enrollment
50
Registered
2022-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium sulfate: perioperative magnesium sulfate infusion will be given to patients at dose of 15mg/kg/hr.blood sugar levels, potassium and magnesium will be measured at specified ti

Sponsors

DR Sampurnanand Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: all patients with adult age group and both sex with diabetes mellitus irrespective of the previous glycemic index control, but controlled baseline blood sugar levels in the past 24 hours of the surgery, LVEF > 40% presenting for cardiac surgery using CPB under general anaesthesia will be included in the study.

Exclusion criteria

Exclusion criteria: patients with congestive heart failure, acute myocardial failure, emergency cases, redo cases, malfunctioning artificial heart valve,obstructive cardiomyopathy, heart rate <50bpm, pericardial disease, renal impairment, hepatic impairment.

Design outcomes

Primary

MeasureTime frame
to see the effect of magnesium sulfate infusion in reducing the blood sugar levlsTimepoint: 0 min, 10 min after induction, before cardiopulmonary bypass, 30 min afte CPB, ICU admsiion, 6 hours after ICU admission,12 hours after admission, 24 hours after admission—

Secondary

MeasureTime frame
blood potassium levels, blood magnesium levels, total requirement of insulin hospital stay, hemodynamic chasnges, side effect of drugTimepoint: 0 min, 10 min after induction, before cardiopulmonary bypass, 30 min afte CPB, ICU admsiion, 6 hours after ICU admission,12 hours after admission, 24 hours after admission—

Countries

India

Contacts

Public ContactAnkur Jain

Rajasthan Medical Council

dr.rakeshkarnawat@yahoo.com9828033321

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026