Health Condition 1: A15- Respiratory tuberculosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a) Freshly confirmed cases of pulmonary tuberculosis (by smear microscopy/CBNAAT). (b) Age > 18years
Exclusion criteria
Exclusion criteria: a) Pulmonary TB patients with other respiratory co-morbidities like co-infections,COPD, lung cancer and interstitial lung disease. (b) Disseminated TB (c) Hemodynamically unstable patients d) Patients who are taking vitamin D supplementation, oral corticosteroids or otherImmunosuppressants or drugs known to interfere with vitamin D levels orinterfere with anti- tubercular drugs (phenytoin, phenobarbital, carbamazepine,theophylline) will be excluded from the study. (e) Patients having extra pulmonary TB, Human Immunodeficiency Virus (HIV) infection,hepatic disease, renal failure, malignancy, pregnancy, sarcoidosis, hyperparathyroidismand history of hypercalcemia will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To see effects of vitamin d supplementation on interleukin 6 levelsTimepoint: To see effects of vitamin d supplementation after 2 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To see effects of vitamin d supplementation on sputum smear negative conversion rateTimepoint: after 2 months of vitamin D supplementation | — |
Countries
India
Contacts
Punjab university