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To see the effects of vitamin D in addition to anti-tubercular treatment on inter-leukin 6 levels in patients having pulmonary tuberculosis

Effects of Vitamin D supplementation on IL-6 levels in patients of Pulmonary Tuberculosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040458
Enrollment
50
Registered
2022-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A15- Respiratory tuberculosis

Interventions

Intervention1: Vitamin D soft gel capsules: Freshly confirmed cases of pulmonary tuberculosis (by smear microscopy/CBNAAT) reporting to DOTS center in-pulmonary medicine OPD who gi

Sponsors

Department of pulmonary medicine GMCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Freshly confirmed cases of pulmonary tuberculosis (by smear microscopy/CBNAAT). (b) Age > 18years

Exclusion criteria

Exclusion criteria: a) Pulmonary TB patients with other respiratory co-morbidities like co-infections,COPD, lung cancer and interstitial lung disease. (b) Disseminated TB (c) Hemodynamically unstable patients d) Patients who are taking vitamin D supplementation, oral corticosteroids or otherImmunosuppressants or drugs known to interfere with vitamin D levels orinterfere with anti- tubercular drugs (phenytoin, phenobarbital, carbamazepine,theophylline) will be excluded from the study. (e) Patients having extra pulmonary TB, Human Immunodeficiency Virus (HIV) infection,hepatic disease, renal failure, malignancy, pregnancy, sarcoidosis, hyperparathyroidismand history of hypercalcemia will be excluded.

Design outcomes

Primary

MeasureTime frame
To see effects of vitamin d supplementation on interleukin 6 levelsTimepoint: To see effects of vitamin d supplementation after 2 months

Secondary

MeasureTime frame
To see effects of vitamin d supplementation on sputum smear negative conversion rateTimepoint: after 2 months of vitamin D supplementation

Countries

India

Contacts

Public ContactPrabhnoor Singh Aulakh

Punjab university

Pulmed1994@gmail.com9646121622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026