Health Condition 1: J17- Pneumonia in diseases classified elsewhere
Conditions
Sponsors
Indraprastha apollo hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. duration of mechanical ventilation more than or equal to 48h 2. age more than or equal to 18 3. clinical suspicion of VAP based on two or more of the following criteria : A. body temperature > 38 C or B. white blood cells > 10000 or C. purulent tracheal secretions D. PaO2/Fio2 < 300
Exclusion criteria
Exclusion criteria: ongoing pneumonia subcutaneous emphysema thoracic dressings pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In patients with clinical suspicion of ventilator associated pneumonia(VAP) , diagnostic performance of combination of lung ultrasound plus S.procalcitonin for diagnosis of VAP will be assessed by sensitivity, specificity , positive predictive value and negative predictive value and compared with white blood cells, procalcitonin , C-reactive protien or Clinical pulmonary infection score alone.Timepoint: only those patients who are on mechanical ventilation for than or equal to 48hours with clinical suspicion of ventilator associated pneumonia will be included in the study . baseline test that will be done at inclusion of patient in the study.no further follow up is required: lung ultrasound procalcitonin CRP Tracheal aspirate for culture and stains chest x ray chest CT ( ONLY IF ADVISED FOR TREATMENT) White blood cells | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitivity , specificity and diagnostic accuracy of lung ultrasound and procalcitonin in comparison to white blood cell count, Procalcitonin , C Reactive protein or clinical pulmonary infection score aloneTimepoint: time frame : upto 30days | — |
Countries
India
Contacts
Public ContactShivali Sandal
Indraprastha Apollo hospital Delhi
Outcome results
None listed