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Effectiveness of type 1 collagen in extraction socket healing

Effect of type 1 collagen in healing of extraction socket after surgical removal of impacted mandibular third molar in comparison to sole blood clot- A randomised controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040407
Enrollment
10
Registered
2022-02-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Type 1 Collagen: Healing agent used in extraction wound Control Intervention1: Blood clot: Normal healing mechanism Same day.

Sponsors

Dr Rinsha Paul
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients requiring surgical removal of bilateral impacted (MESIOANGULAR) mandibular third molars with a relatively similar classification and degree of difficulty based on Pell and Gregory and Winterââ?¬•s system of classification. 2. Patients with no systemic diseases or conditions -American society of anaesthesiology- ââ?¦Â  (ASA) 3. Patients consent to undergo surgical procedure and to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with systemic diseases. 2. Patients with bleeding disorders. 3. Patients on antiplatelet or anticoagulant therapy 4. Nursing or pregnant women. 5. History of allergy to lignocaine and commonly used drugs. 6. Patients with local infections such as pericoronitis. 7. Patients with previous history of TMJ problems 8. Patients not willing to participate.

Design outcomes

Primary

MeasureTime frame
Wound healingTimepoint: 3rd, 5th and 7th postoperative day

Secondary

MeasureTime frame
Bone mineralisationTimepoint: 1st month, 4th month;Periodontal pocket depthTimepoint: 1month, 4th month;Postoperative trismusTimepoint: 3rd, 5th and 7th day;Postoperative painTimepoint: 3rd, 5th and 7th postoperative day;Postoperative swellingTimepoint: 3rd, 5th and 7th postoperative day

Countries

India

Contacts

Public ContactDr Rinsha Paul

Government Dental College, Kottayam

drpgantony@yahoo.com9447258110

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026