FindTrial
Sign In

Comparison of a blood derived product and a dressing processed from animal skin for treatment of receded gums.

Coronally advanced flap with platelet rich fibrin or xenogeneic collagen matrix for the treatment of multiple adjacent gingival recession defects: A randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040385
Enrollment
20
Registered
2022-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: K055- Other periodontal diseases

Interventions

Intervention1: Xenogenic collagen matrix (XCM): The matrix of desired dimensions will be trimmed and applied in a dry state on the affected teeth at the level of the cemento-enamel junction and stabi

Sponsors

Centre for Dental Education and Research All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) systemically healthy individuals b) Healthy periodontium or demonstrating stable periodontal condition following conventional periodontal therapy c) Full mouth plaque score (FMPS) and full mouth bleeding score (FMBS) of d) No history of previous periodontal surgery at experimental sites e) Presence of at least two adjacent Cairo RT1 (gingival recession with no loss of interproximal attachment) multiple buccal recessions >= 2 mm on anterior teeth or premolars in both jaws f) Presence of an identifiable CEJ (a step g) Probing depth (PD) h) Absence of non-vital, supraerupted or mobile teeth for treatment of GR.

Exclusion criteria

Exclusion criteria: a) Molars and teeth with presence of restorations, caries or crowns in the area to be treated. b) Gingival recessions presenting minimal amount ( c) Pregnant and lactating females d) Smokers or tobacco usage in any form e) History of any systemic medication in last 3 months f) Patients with coagulation disorders

Design outcomes

Primary

MeasureTime frame
To compare and evaluate effectiveness of xenogeneic collagen matrix or platelet rich fibrin with modified coronally advanced flap procedure in terms of gingival recession reduction and soft tissue thickness gain after either treatment.Timepoint: 3, 6 months and 1 year—

Secondary

MeasureTime frame
Objective assessment of aesthetic outcome using root coverage esthetic score (RES) To assess any differences in patient- centered outcome in terms of postsurgical pain till 1 week and dentinal hypersensitivity and aesthetic satisfaction.Timepoint: baseline, 3, 6 months and 1 year—

Countries

India

Contacts

Public ContactVikender Yadav

All India Institute of Medical Sciences

vikenderyadav@gmail.com8800798248

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026