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effectiveness of ketamine and propofol on prevention of muscle pain caused after the use of succinyl choline during surgeries

Effect of Pretreatment with Propofol and Ketamine on Succinylcholine induced Mayalgia: A Comparative study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040300
Enrollment
54
Registered
2022-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: in. propofol {neorof 20ml vial} 200mg: 0.5mg/kg, intravenous Intervention2: NIL: NIL Control Intervention1: Injection ketamine: To check the effect of drug on succinyl choline induced p

Sponsors

Dr Akanksha bharat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA Grade 1,2 2. Age 18 to 65 years 3. Both males and females 4. elective surgeries under general anesthesia with endotracheal intubation under effects of succinyl choline 5. Surgeries completed within 3 hrs

Exclusion criteria

Exclusion criteria: 1. Patient with contraindication to succinyl choline use like chronic deblitating illness, raised intracranial tension, myopathy, recent burns{ 2. Pregnant patients and lactating mothers 3. Patients with severe cardiovascular, liver or renal disease 4. Morbid obesity{BMI >35} 5. Patients with known allergies to the study drug 6. Patients who has received analgesic+ muscle relaxants medication in last 24 hrs

Design outcomes

Primary

MeasureTime frame
To study and compare following parameters in both the groups 1. Severity of fasiculations after succinylcholine administration 2. Incidence of post operative myalgia 3. Severity of post operative myalgia after 24hours and 48 hoursTimepoint: After induction agent for severity of fasiculations, Post operatively 24 and 48 hours

Secondary

MeasureTime frame
To study and compare haemodynamic parameters (heart rate and mean arterial pressure) in both groupsTimepoint: Intra operetively 0,2,4,6 minute before induction agent, Intra operatively 0,5,10 minute after intubation

Countries

India

Contacts

Public ContactDr Akanksha Bharat

MGM medical college, aurangabad

vasantikelkar70@gmail.com9370668196

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026