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Comparison of effect of nebulising magnesium sulphate with lignocaine before the start of surgery in decreasing the response to endotracheal intubation in patients

Efficacy and comparison of Nebulised Magnesium Sulphate with lignocaine in blunting Hemodynamic response to Endotracheal Intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/040216
Enrollment
78
Registered
2022-02-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulization with Magnesium sulphate: nebulization with 200mg magnesium suphate done, 15 minutes before induction of general anaesthesia, to check haemodynamic response during endotrach

Sponsors

Dr Harsmeet Kaur Bhinder
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA1 &ASA2 Patient undergoing elective surgery in general anaesthesia of duration less than 2 hours No history of allergy to lignocaine or magnesium sulphate Systolic BP >100mmhg and heart rate > 50bpm No anticipated difficult airway

Exclusion criteria

Exclusion criteria: Refusal of consent by patient

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure Systolic blood pressure Diastolic blood pressure Heart rate SpO2Timepoint: 0min While nebulising 5min 10min 15 min Before induction Post intubation 1min 3min 5min 7min 10min—

Secondary

MeasureTime frame
Grading of sore throat after 24hours of surgeryTimepoint: Grade1- c/o sore throat only on asking Grade 2- c/o sore throat on his her own Grade3- c/o change in voice or pain in throat—

Countries

India

Contacts

Public ContactDr Harsmeet Kaur Bhinder

Indira Gandhi Medical college, Shimla

drdaranegi@gmail.com9418059643

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026