Exercise, nutrition and mental well being support in reducing complications after surgery for cancer of ovary.

Pre-habilitation in ovarian cancer cytoreductive surgery and its effect on postoperative morbidity (PROSPERITY): A randomized controlled trial - PROSPERITY

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/02/040212

Enrollment

120

Registered

2022-02-11

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C569- Malignant neoplasm of unspecifiedovary

Interventions

Intervention1: Prehabilitation group: Exercise therapy Strengthening activity will be prescribed 3 days per week, which includes exercises for 8 muscle groups for 30 minutes (including 5-minute warm

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age > 18 years 2. Patients awaiting elective cytoreductive surgeries for ovarian cancer after completion of the due course of chemotherapy. 3. Time to surgery 2 to 6 weeks.

Exclusion criteria

Exclusion criteria: 1. Laparoscopic surgery 2. Heart disease with positive stress test 3. Chronic pulmonary disease with dyspnoea at exertion. 4. Limb immobility 5. Hemoglobin 6. Acute infection 7. Known hypersensitivity to any drugs or to parenteral iron 8. Bronchial asthma 9. Chronic liver disease with SGOT, SGPT >3 times the upper limit of normal 10. Renal disease requiring dialysis 11. Inability to comprehend and perform the exercise interventions 12. Active bleeding from tumour 13. Massive ascites /pleural effusion refractory after the last cycle of chemotherapy 14. Patients for primary surgery will be excluded.(Surgery before chemotherapy)

Design outcomes

Primary

Measure	Time frame
The primary outcomes are 30 day comprehensive complication index in the two groups. It will be assessed based on a online tool. (https://www.assessurgery.com/about_cci-calculator/ )Timepoint: The primary outcomes are 30 day comprehensive complication index in the two groups. It will be assessed based on a online tool. (https://www.assessurgery.com/about_cci-calculator/ )	—

Secondary

Measure	Time frame
To compare, in patients undergoing ovarian cytoreductive surgeries, prehabilitation and conventional care with respect to 1. Six minute walk test- assessed on day before surgery and four weeks after surgery. 2. QOL- assessed on day before surgery, at discharge from hospital and four weeks after surgery. 3. Length of ICU stay 4. Perioperative blood transfusion- packed red cell transfusion within 2 weeks of surgery. Timepoint: day before surgery, at discharge and 4 weeks after surgery	—

Measure

Time frame

To compare, in patients undergoing ovarian cytoreductive surgeries, prehabilitation and conventional care with respect to 1. Six minute walk test- assessed on day before surgery and four weeks after surgery. 2. QOL- assessed on day before surgery, at discharge from hospital and four weeks after surgery. 3. Length of ICU stay 4. Perioperative blood transfusion- packed red cell transfusion within 2 weeks of surgery. Timepoint: day before surgery, at discharge and 4 weeks after surgery

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Countries

India

Contacts

Public ContactDr Prasanna Vani Vanamail

Cancer Institute (W.I.A.)

prasna.vani@gmail.com8946042271

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026