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study of role of intravenous bolus followed by infusion of Dexmedetomidine to evaluate hemodaynamic stability during laryngoscopy and endotracheal intubation

An observetional study of role of intravenous bolus followed by infusion of dexmedetomidine for attenuation of pressor response to laryngoscopy and endotracheal intubation.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/02/040193
Enrollment
62
Registered
2022-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

Shree Krishna hospitalAnand
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients ASA (American society of anesthesiologists) 1-3 physical status 2) Age 18-75yrs of either sex 3) Patient scheduled for elective & emergency surgical procedure under general anaesthesia

Exclusion criteria

Exclusion criteria: 1) Hypersensitivity to dexmedetomidine 2)Advanced heart blocked (grade 2 or 3) 3)Uncontrolled hypotension 4) Pregnancy 5) Severe pulmonary, hepatic, cardiac or renal diseases. 6)BMI > 40 kg/m2 7) Mouth opening less than 1.5 fingers 8) Baseline HR 9)intubation lasting longer than 15 seconds Multiple intubation attempts (2 or more)

Design outcomes

Primary

MeasureTime frame
Hemodynamics stability within 20% of the baseline hemodynamic parameters with intravenous bolus followed by infusion of dexmedetomidine for laryngoscopy and endotracheal intubationTimepoint: 0,1,3,5,7,10,15 minutes—

Secondary

MeasureTime frame
Complications of laryngoscopy and intubationTimepoint: 0,1,3,5,7,10,15 minutes post intubation—

Countries

India

Contacts

Public ContactDr Sandhya Patel

H M Patel centre for medical care and education

nspole2663@gmail.com7984792708

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026