Health Condition 1: J189- Pneumonia, unspecified organism
Conditions
Interventions
Intervention1: intravenous steroid- Inj Dexamethasone: Inj Dexamethasone
day 1- 0.6 mg/kg ,
day2 -0.6 mg/kg
day3 -0.3 mg/kg
day4 -0.15 mg/kg
Control Intervention1: Standard care: No dexamethasone ,
Sponsors
Dr Mehta Childrens hospital
Eligibility
Inclusion criteria
Inclusion criteria: All consecutive children aged 1month to 60 months admitted to PICU with ââ?¬Å?severe pneumonia requiring oxygen therapyââ?¬? would be enrolled in this study after getting informed consent from parents.
Exclusion criteria
Exclusion criteria: 1.Children diagnosed to have chronic lung disease 2.Any child hospitalized for respiratory illness in last one month period 3.Children previously diagnosed to have bronchial asthma 4.Children receiving home mechanical ventilation 5.Children diagnosed to have preexisting neuromuscular disease 6.Children diagnosed to have pre existing adrenal insufficiency 7.Children diagnosed to have empyema at admission to emergency room 8.Children diagnosed to have pre existing immunocompromised conditions 9.Children diagnosed to have Tuberculosis before admission
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Rise in secondary infections , Complications like - hyperglycemia , Gastrointestinal bleeding , hypertension .Timepoint: Till the time child is admitted in PICU | — |
Primary
| Measure | Time frame |
|---|---|
| The primary outcome parameter in patients after randomisation to steroid and placebo group is the duration of oxygen therapy ( in hours) during the first 5 days of admissionTimepoint: The primary outcome parameter in patients after randomisation to steroid and placebo group is the duration of oxygen therapy ( in hours) during the first 5 days of admission | — |
Countries
India
Contacts
Public ContactAiswarya Sankar
Dr Mehta Childrens Hospital
Outcome results
None listed