Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue
Conditions
Interventions
None listed
Sponsors
Science and Engineering Research Board SERB
Eligibility
Inclusion criteria
Inclusion criteria: Case :Adult ( > 18 years) 1.Should have undergone an orthopaedic trauma surgery (with or without orthopaedic implants) and should have developed clinical signs of surgical site infection, within three weeks (early in-fection) post-operatively. 2.Should have a positive microbial culture 3.Should be willing to participate in the study Controls: Adult post-operative orthopaedic trauma patients with negative wound cultures and no cli-nico-radiological signs/symptoms of infection will be included as controls.
Exclusion criteria
Exclusion criteria: Exclusion Criteria 1.Children ( 2.Infections beyond 3 weeks. 3.Culture negative patients 4.Acute flare up of chronic infections 5.Patients in renal, hepatic or cardiac failure. 6.Patients with congenital or acquired immunodeficient states. 7.Patient not willing to give consent / participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To develop a diagnostic tool for early detection of the surgical site infection with serological markers.Timepoint: 6-24 months | — |
Secondary
| Measure | Time frame |
|---|---|
| to develop a new tool to predict and detect SSI at the early stage and an appropriate early intervention can be taken to prevent the fulminant infection.Timepoint: 18-24 months | — |
Countries
India
Contacts
Public ContactDr Prasoon Kumar
Post graduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed