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Anaemia and acid base parameters

Relationship between severity of anaemia and acid base parameters - a pilot study. - ANABP study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/02/039987
Enrollment
100
Registered
2022-02-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E611- Iron deficiency Health Condition 2: R710- Precipitous drop in hematocrit

Interventions

Control Intervention1: Nil: Nil

Sponsors

AIIMS Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-65 years 2. Either Sex 3. Hb levels 4. Belonging to ASA grade I & II

Exclusion criteria

Exclusion criteria: 1. Patients aged 65 years 2. ASA grade III and above. 3. Patients with Hb > 10.9gm/dl. 4. Patients having any major illness or uncontrolled co-morbidity 5. Inability/unwillingness to give consent (e.g mental retardation etc) 6. All known causes of acid-base imbalances (confounding factors) such as seizures, neuromuscular disorders, reduced cardiac output, shock, PDA, heart failure, renal disease, renal failure, renal replacement therapy, gastrointestinal disease, dehydration, diarrhoea, vomiting, burns, supplementary feeds, asphyxia, hypoxemia, severe asthma, COPD, alcoholism, cancer, liver failure, abnormal LFT, carbon monoxide poisoning fever, sepsis, medicines such as salicylates, metformin, antiretrovirals, diuretics, ACEIâ??s, etc., low blood sugar, (hypoglycemia), exercising vigorously for a very long time, hypothermia, inborn error of metabolism, IV fluid therapy, diabetics, diabetic ketoacidosis poisonings, etc.

Design outcomes

Primary

MeasureTime frame
To determine the relationship between a given Hb level below 10.9 g/dl and change in pH from the normal range i.e delta pH on a venous blood gas analysis.Timepoint: Outcome will be assessed co-relating the baseline value of Hb (less than 10.9g/dl) and ABG only.

Secondary

MeasureTime frame
To determine the relationship between a given Hb level below 10.9 g/dl and change in HCO3, base excess and lactate level from the normal range i.e delta HCO3, delta base excess and delta lactate levels on a venous blood gas analysis.Timepoint: Outcome will be assessed co-relating the baseline value of Hb (less than 10.9g/dl) and ABG only.

Countries

India

Contacts

Public ContactDr Sarita Ramchandani

AIIMS, Raipur.

drsaritaramchandani@gmail.com9424204244

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026