Health Condition 1: D- Radiation Therapy
Conditions
Interventions
Intervention1: Intravenous Ketamine: 1mg/kg Pre-procedure
0.5mg/kg boluses intraprocedural guided by Pediatric Sedation State Scale ,Face Legs Activity Cry Consolability Scale and bispectral index
C
Sponsors
Rajiv Gandhi Cancer Institute and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: Undergoing External Beam Radiotherapy under Sedation
Exclusion criteria
Exclusion criteria: No parental consent Retinoblastoma Radiation simulation Raised Intracranial Pressure Allergic to study drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pediatric Sedation State ScaleTimepoint: 0 minutes Baseline preprocedural 3 minutes after injection of intervention/comparator drug 6 minutes after injection of intervention/comparator drug 9 minutes after injection of intervention/comparator drug 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart RateTimepoint: 0 minutes Baseline preprocedural 3 minutes after injection of intervention/comparator drug 6 minutes after injection of intervention/comparator drug 9 minutes after injection of intervention/comparator drug 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure;Arterial oxygen SaturationTimepoint: 0 minutes Baseline preprocedural 3 minutes after injection of intervention/comparator drug 6 minutes after injection of intervention/comparator drug 9 minutes after injection of intervention/comparator drug 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure;Face Legs Activity Cry Consolibility ScaleTimepoint: 0 minutes Baseline preprocedural 3 minutes after injection of intervention/comparator drug 6 minutes after injection of intervention/comparator drug 9 minutes after injection of intervention/comparator drug 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure;Bispectral IndexTimepoint: 0 minutes Baseline preprocedural 3 minutes after injection of intervention/comparator drug 6 minutes after injection of intervention/comparator drug 9 minutes after injection of intervention/comparator drug 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure;Respiratory RateTimepoint: 0 minutes Baseline preprocedural 3 minutes after injection of intervention/comparator drug 6 minutes after injection of intervention/comparator drug 9 minutes after injection of intervention/comparator drug 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure;Richmond Agitation Sedation ScaleTimepoint: 0 minutes post-procedure 10 minutes post-procedure 30 minutes post-procedure | — |
Countries
India
Contacts
Public ContactDr Swati Sahay
Rajiv Gandhi Cancer Institute and Research Centre
Outcome results
None listed