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A clinical trial to compare the effect of two sleep causing drugs namely etomidate and propofol-phenylephrine combination on heart rate and blood pressure in adult patients undergoing open heart surgeries

Hemodynamic profiles of etomidate vs propofol-phenylephrine combination for induction of anaesthesia in adult cardiac surgical patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/02/039898
Enrollment
64
Registered
2022-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: I052- Rheumatic mitral stenosis with insufficiency

Interventions

None listed

Sponsors

Molli Kiran
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult ASA II-IV patients undergoing elective cardiac surgeries involving valve replacement and/or coronary artery bypass grafting surgeries who are willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with known allergy to the study drugs 2. Emergency surgeries 3. Patients with anticipated difficult airway and patients who require more than 2 attempts or more than 30 seconds for direct laryngoscopy

Design outcomes

Primary

MeasureTime frame
1.Heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure every 30 sec for the first ten minutes after inductionTimepoint: first ten minutes after anaesthesia induction

Secondary

MeasureTime frame
number of extra doses of phenyl ephrine needed in both the groupsTimepoint: first ten minutes of induction

Countries

India

Contacts

Public ContactMolli Kiran

All India Institute of Medical Sciences, Bhopal

mvr934@gmail.com9441497323

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026