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Comparative study of postoperative outcomes of anesthesia technique using non opioid drugs with that of conventional anesthesia technique using opioid drugs among adult patients undergoing elective laparoscopic cholecystectomy.

Comparison of opioid free anesthesia with opioid based anesthesia for laparoscopic cholecystectomy: a double blinded randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/02/039883
Enrollment
88
Registered
2022-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: opioid free anesthesia: patients are provided opioid free anesthesia. dexmedetomidine infusion will be started at a dose of 0.5 mcg/kg/hr 10 minutes prior to induction for sedation. pat

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of anesthesiologist physical status 1 and 2. 2. adult patients posted for elective laparoscopic cholecystectomy. 3. body mass index 18.5 to 34.9

Exclusion criteria

Exclusion criteria: 1. body mass index >35 kg/m2. 2. pregnant and breastfeeding women. 3. history of any hepatic, renal, cardiac disease. 4. history of alcohol abuse, drug abuse, psychiatric illness. 5. history of chronic pain( pain present for more than 6 months).

Design outcomes

Primary

MeasureTime frame
to compare the cumulative amount of fentanyl used for pain relief in first 6hours after extubation of adult patients undergoing elective laparoscopic cholecystectomy in opioid free anesthesia and opioid based anesthesia groups.Timepoint: 2hours, 6hours, 12hours, 24hours after extubation.—

Secondary

MeasureTime frame
1. to assess the postoperative pain scores using numerical rating scale at 2hours, 6hours, 12hours and 24hours after extubation. 2. to find the amount of intravenous fentanyl consumed by the patients as a rescue analgesic at 2hours, 12hours and 24hour postoperative periods. 3. to find the time taken by the patients for the first time use of intravenous fentanyl rescue analgesia after extubation. 4. to find the incidences of postoperative nausea and vomiting episodes experienced by the patients in first 24hour postoperative period. 5. to document any other postoperative complications experienced by the patients in first 24hour postoperative period. among patients in both the groups.Timepoint: first 24 hour postoperative period after extubation.—

Countries

India

Contacts

Public ContactVishnuraj K R

All India Institute of Medical Sciences Patna

drsinghkunal@gmail.com9411514945

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026