Health Condition 1: K044- Acute apical periodontitis of pulpal origin
Conditions
Interventions
Intervention1: Simvastatin: Simvastatin has proven to be extremely useful in the treatment of vertical root fractures. its role as an anti-inflammatory agent is well known. There are various in-vitro
Sponsors
Manan Shroff
Eligibility
Inclusion criteria
Inclusion criteria: 1. A mature permanent single-rooted single-canal tooth with intact pulp chamber walls. 2. Necrotic pulps as confirmed by negative response to sensitivity pulp tests. 3. Clinical and radiographic evidence of apical periodontitis. 4. Patients suffering from apical periodontitis with lesion size
Exclusion criteria
Exclusion criteria: 1. Patients suffering from a significant systemic condition. 2. Patients who received antibiotic therapy within the previous 3 months 3. Teeth with calcified pulp chamber 4. Teeth with vertical root fracture 5. Teeth which had received previous endodontic treatment 6. Cases showing periodontal pockets deeper than 4mm. 7. Patients on medications such as chemotherapy, anticoagulants, corticosteroids, bisphosphonates and immunosuppressant drugs 8. Patients who have chronic diseases decompensated (e.g. hypertension, diabetes, rheumatic diseases, renal, and hepatic) 9. Patients with bone diseases, metabolic (osteomalacia, hypocalcemia and hypercalcemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ï??The result of this study will help us to know about the antibacterial efficacy of simvastatin as intracanal medicamentTimepoint: ï??First sample will be taken at baseline. Second sample will be taken after a week (7 days) | — |
Secondary
| Measure | Time frame |
|---|---|
| To know which has better antibacterial activity between simvastatin and double antibiotic pasteTimepoint: 7 days | — |
Countries
India
Contacts
Public ContactDr Kishan KV
Professor and Post Graduate Guide, K.M Shah Dental College and Hospital
Outcome results
None listed