A study to compare difference between effect of addition of clonidine to ropivacaine in epidural anaesthesia

A comparative study of clonidine as adjuvant to ropivacaine and ropivacaine alone in epidural anesthesia for lower limb surgeries

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039791

Enrollment

Registered

2022-01-28

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Epidural Clonidine: Two groups will be made one group will receive 19 ml of 0.75% ropivacaine + 1 ml of normal saline (20 ml) and second group will receive 19 ml of 0.75% ropiva

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients aged between 18 to 65 years of both sex. 2.Patients belonging to ASA class I and II posted for elective lower limb surgical procedures.

Exclusion criteria

Exclusion criteria: 1.Patient refusal for regional anaesthesia. 2.Pregnancy and lactation. 3.Obese patient with BMI > 30. 4. Contraindication to regional anaesthesia 5.Allergy to local anaesthetics 6.Allergy to study drugs

Design outcomes

Primary

Measure	Time frame
1. To evaluate effect of ropivacaine alone in epidural anaesthesia for lower limb surgeries. 2. To evaluate effect of clonidine as adjuvant to ropivacaine in epidural anaesthesia for lower limb surgeries. 3. To compare effect of ropivacaine alone and clonidine as adjuvant to ropivacaine in epidural anaesthesia for lower limb surgeries. Timepoint: surgery is allowed till sensory level reach t8 and vital readings taken every 5 min till surgery goes on then hourly upto 6 hour, 2 hourly uto 12 hour then every 4 hourly upto 24 hour	—

Measure

Time frame

1. To evaluate effect of ropivacaine alone in epidural anaesthesia for lower limb surgeries. 2. To evaluate effect of clonidine as adjuvant to ropivacaine in epidural anaesthesia for lower limb surgeries. 3. To compare effect of ropivacaine alone and clonidine as adjuvant to ropivacaine in epidural anaesthesia for lower limb surgeries. Timepoint: surgery is allowed till sensory level reach t8 and vital readings taken every 5 min till surgery goes on then hourly upto 6 hour, 2 hourly uto 12 hour then every 4 hourly upto 24 hour

—

Secondary

Measure	Time frame
time till onset of sensory block time till onset of motor blockTimepoint: time till onset of sensory block time till onset of motor block then monitoring every 5 min till surgery goes on and every hour till 6 hour, then 2 hourly upto 12 hour then 4 hourly till 24 hour	—

Countries

India

Contacts

Public ContactDr Mukesh Kumar

GGS Medical College and Hospital Faridkot

mukeshktala@gmail.com9464887097

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026