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Estimations of Substance-P level in patients with Degenerative Lumbar spine disease undergoing Decompressive Surgery

Substance-P level in Subjects with Degenerative Lumbar spine Disorder Undergoing Decompressive Surgery- A comparative study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/01/039780
Enrollment
58
Registered
2022-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G544- Lumbosacral root disorders, not elsewhere classified

Interventions

Control Intervention1: NA: NA Control Intervention2: Substance-P level in Subjects with Degenerative Lumbar spine Disorder: Substance-P level in Subjects with Degenerative Lumbar spine Disorder Unde

Sponsors

Amrita Panda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. H or O low back pain for 3 months 2. Posted for decompressive spine surgery

Exclusion criteria

Exclusion criteria: 1.ASA-3&4 Pts 2.H/O other chronic pain syndromes 3.H/O trauma 4.Pregnancy 5. H/O ACE/ ARB

Design outcomes

Primary

MeasureTime frame
estimation of substance of p level in patients 24 hours prier to surgery, 5th day: post operative day and 8 weeks day of dischargeTimepoint: 0 weeks - 8 weeks

Secondary

MeasureTime frame
Correlation of S-P with other parameters of acute pain like NPS,Haemodynamics. Assosciation with age,gender,h/o pain duration,types of decompressive spine surgery. Timepoint: 6 months

Countries

India

Contacts

Public ContactAmit Pradhan

Kalinga institute of medical sciences

amrita.panda@kims.ac.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026