Health Condition 1: O141- Severe pre-eclampsia
Conditions
Interventions
Intervention1: study group of 12 hour duration: All enrolled patients of study will receive loading dose of MgSO4, 4 gm intravenously. The dose will be constituted by diluting 8 mL of 50% MgSO4 soluti
Sponsors
DMIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients of severe pre-eclampsia, with blood pressure 160/100 mm of Hg and proteinuria 3+ or more 2. singleton pregnancy 3. patients willing to participate in study
Exclusion criteria
Exclusion criteria: 1. Age of patient 2. Patients with either antepartum or intrapartum or postpartum convulsions(before enrollment) 3. Patients with known case of epilepsy 4. Patients with renal or liver disorder, not attributed to preeclampsia 5. Central Nervous System disorder 6. Chronic kidney disease 7. Seizures due to metabolic disturbances, space occupying lesions or intra cerebral infections 8. Cardiac patients 9. Contraindications to MgSO4 i.e. drug hypersensitivity, myasthenia gravis, anuria or oliguria 10. Prior intake of any other anticonvulsant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurence of seizures in next 24 hours after completion of intervention in both groupsTimepoint: 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events/side effects in both groupsTimepoint: 24 hours;Need to prolong therapy of magnesium sulfate for 24 hoursTimepoint: 24 hours;Recovery of patients (first 48 hours) in both groups in terms of Length of HDU stay Early ambulation Duration of indwelling catheter Mother to baby caring/roomin Timepoint: 48 hours | — |
Countries
India
Contacts
Public ContactAmruta Choudhary
JNMC and AVBRH, Sawangi,Wardha
Outcome results
None listed