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Hypertonic saline nebulisation in neonatal ventilator associated pneumonia

Prevention of ventilator associated pneumonia using hypertonic saline nebulisation in neonatal intensive care unit: A randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039755
Enrollment
300
Registered
2022-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P228- Other respiratory distress of newborn

Interventions

Intervention1: Hypertonic Saline: 12 hourly nebulisation with HYPERTONIC SALINE will be done of ventilated patients via the nebuliser attachment of the ventilator Control Intervention1: ROUTINE CARE.:

Sponsors

MLN MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Newborns on ventilator

Exclusion criteria

Exclusion criteria: Established pneumonia Hypernatremia Congenital anomalies of respiratory tract Pulmonary hemorrhage DIC Previous mucolytic prescription

Design outcomes

Primary

MeasureTime frame
COMPARISION OF mCPIS SCORETimepoint: at extubaion or at 7 days after intubation; whichever is earlier—

Secondary

MeasureTime frame
1 Duration of stay on ventilator 2 Side effects of hypertonic saline nebulization 3 MICROBIOLOGICAL PROFILE OF VAPTimepoint: 1 year—

Countries

India

Contacts

Public ContactDR ARPIT GUPTA

MLN MEDICAL COLLEGE PRAYAGRAJ

anubhashrivastava@rediffmail.com9236804326

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026