Health Condition 1: H712- Cholesteatoma of mastoid Health Condition 2: H701- Chronic mastoiditis Health Condition 3: J320- Chronic maxillary sinusitis Health Condition 4: K119- Disease of salivary gland, unspecified Health Condition 5: K111- Hypertrophy of salivary gland Health Condition 6: C509- Malignant neoplasm of breast of unspecified site Health Condition 7: C55- Malignant neoplasm of uterus, partunspecified Health Condition 8: E042- Nontoxic multinodular goiter Health Condition 9:
Conditions
Interventions
Intervention1: nebulisation: dexmedetomidine 1 microgram per kg body weight in 5 ml NS to one group and 5 ML normal saline to other group
Sponsors
DR THOMAS GEORGE
Eligibility
Inclusion criteria
Inclusion criteria: ASA(American Society of Anaesthesiologist) Grade 1 ASA(American Society of Anaesthesiologist) Grade 2 Patients undergoing General Anaesthesia
Exclusion criteria
Exclusion criteria: Pregnant and lactating women Haemodynamically compromised patients Emergency patients Patients on alpha and beta blocker Patients sensitive /allergic to study medication Patients with hyper-reactive airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparison of haemodynamic stress response such as heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure will be measured before and after giving the nebulisation and the same is checked at every 1, 5, 10 minutes after the intubation . sore throat will be evaluated at 0,2,4,6,12 and 24h after extubation, during the post-operative period with dexmedetomidine and saline nebulisationTimepoint: 1 day | — |
Secondary
| Measure | Time frame |
|---|---|
| sore throat will be evaluated at 0,2,4,6,12 and 24h after extubation, during the post-operative period with dexmedetomidine and saline nebulisationTimepoint: 1 day | — |
Countries
India
Contacts
Public ContactDR THOMAS P GEORGE
PUSHPAGIRI INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE
Outcome results
None listed